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This case report presents the case of a 1-year-old female with sickle cell anemia who developed pyomyositis due to Infection with Salmonella species. The clinical presentation of the patient included jaundice, high fever, and pain in the left shoulder, which progressed to redness, swelling, and limitations in movement. An MRI scan was conducted on the patient, revealing fluid loculations in the shoulder muscles. A surgery was performed on the patient. Post-operative care included antibiotics, leading to significant clinical improvement. This report highlights the importance of early diagnosis and the appropriate management of pyomyositis in patients with underlying conditions, such as sickle cell anemia.

Keywords: Intramuscular abscess; Salmonella species; Sickle cell anemia; Rotator cuff pyomyositis